RNA splicing occurs in the nucleus of eukaryotic cells.

RNA splicing occurs in the nucleus of eukaryotic cells.

• A. True
• B. False
• C. It occurs in mitochondria
• D. It occurs in cytoplasm

Answer: (A)

RNA splicing is the removal of introns from a pre-mRNA transcript and joining of exons, a processing step that happens in the nucleus of eukaryotic cells. The spliceosome, a complex made of small nuclear RNAs and proteins, carries out this editing on newly synthesized transcripts as part of RNA processing. This nuclear location is important because only after introns are removed and the mRNA is capped and polyadenylated does it get exported to the cytoplasm for translation. In contrast, mitochondria generally do not perform this nuclear-type splicing on their transcripts, and the cytoplasm isn’t where splicing occurs. So, RNA splicing occurring in the nucleus is the correct understanding.

RNA splicing is the removal of introns from a pre-mRNA transcript and joining of exons, a processing step that happens in the nucleus of eukaryotic cells. The spliceosome, a complex made of small nuclear RNAs and proteins, carries out this editing on newly synthesized transcripts as part of RNA processing. This nuclear location is important because only after introns are removed and the mRNA is capped and polyadenylated does it get exported to the cytoplasm for translation. In contrast, mitochondria generally do not perform this nuclear-type splicing on their transcripts, and the cytoplasm isn’t where splicing occurs. So, RNA splicing occurring in the nucleus is the correct understanding.