Is it true that the codon of tRNA is complementary to the anticodon of mRNA?

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Multiple Choice

Is it true that the codon of tRNA is complementary to the anticodon of mRNA?

Explanation:
In translation, the anticodon on the tRNA pairs with the codon on the mRNA. There isn’t a codon on tRNA; the tRNA carries an anticodon that is complementary to the mRNA codon to ensure the correct amino acid is added. For example, an mRNA codon 5'-AUG-3' pairs with a tRNA anticodon 3'-UAC-5'. Wobble at the third position adds some flexibility, but the essential relationship is anticodon-to-codon, not codon-to-anticodon on mRNA. So the statement is not accurate.

In translation, the anticodon on the tRNA pairs with the codon on the mRNA. There isn’t a codon on tRNA; the tRNA carries an anticodon that is complementary to the mRNA codon to ensure the correct amino acid is added. For example, an mRNA codon 5'-AUG-3' pairs with a tRNA anticodon 3'-UAC-5'. Wobble at the third position adds some flexibility, but the essential relationship is anticodon-to-codon, not codon-to-anticodon on mRNA. So the statement is not accurate.

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