In translation, which component catalyzes peptide bond formation?

In translation, which component catalyzes peptide bond formation?

• A. tRNA anticodons
• B. mRNA
• C. Ribosome
• D. DNA polymerase

Answer: (C)

Peptide bond formation during translation is carried out by the ribosome. In the elongation step, the growing polypeptide is transferred from the tRNA in the P site to the amino acid on the tRNA in the A site, forming a new peptide bond. This reaction is catalyzed by the ribosome’s peptidyl transferase center, which is formed largely by ribosomal RNA and acts as a ribozyme. The tRNA anticodons ensure the correct amino acids are brought in by pairing with the mRNA codons, the mRNA provides the template sequence, and DNA polymerase is for copying DNA, not translating it. So the ribosome is the catalyst for peptide bond formation.

Peptide bond formation during translation is carried out by the ribosome. In the elongation step, the growing polypeptide is transferred from the tRNA in the P site to the amino acid on the tRNA in the A site, forming a new peptide bond. This reaction is catalyzed by the ribosome’s peptidyl transferase center, which is formed largely by ribosomal RNA and acts as a ribozyme. The tRNA anticodons ensure the correct amino acids are brought in by pairing with the mRNA codons, the mRNA provides the template sequence, and DNA polymerase is for copying DNA, not translating it. So the ribosome is the catalyst for peptide bond formation.